Chronic dark circles under eyes
Urine test called Microbial organic acids test, COLLECTION 11-14-11 sent to the Great Plains Laboratory. This test was an important puzzle piece. Her urine was high in HPHPA Clostirdia, bacterial metabolites. The normal range is <227. Allie's was off the chart, literally, at 2,987. The first round of treatment usually is Vancompycin, Alinia or Flagyl. In the past she was on all three of these for C-Diff. We knew from her past, her behaviors did not improve with this treatment. Allie did, however, respond behaviorally well to the antifungal Fluconizole 100 mg once daily, this is generic for Diflucan. She had more energy, a clear head and less aggression. We cannot have her on fluconizole forever because it is hard on the liver.
Immunoglobulin blood test DRAWN 11-14-11 - measures the level of immunoglobulins (or antibodies) in her blood. The immune system fights off bacteria, viruses, toxins ect. when we are sick. We found after Dr. JK did this blood test she was IgA, IgG, and IgM deficient. The technical term is hypogammaglobulinemia. Here are her results:
IgG antibodies are fond in body fluids that protects against bacterial and viral infections. Which explains her strep infections.
IgM antibodies fight a new infection and are located in the lymph fluid. She does well in this area, her level was on the high/low end.
We made an appointment right away with the best immunologist closest to us in Minnesota. His name is Dr. Mark Schleiss at the U of MN. He was not too concerned! Basically after a 2 hour appointment with him he told us she just is not sick enough for treatment. I understand this doctor see's the sickest kids there is, that is sad. What about my kid? I felt like he was comparing us to so many other kids. After a few months, his fellow, Dr. Hannish did say she has this immune defiency due to her Depakote and Lamictal. The neurologist, does not want to D/C these meds because she would have more seizures if we did D/C those meds. A Catch 22. Dr. Hannish did say she could be prescribed IVIG therapy.
Possible treatment option- IVIG or SCIG - Intravenous & subcutaneous immune globulin therapy. This therapy contains the immune globulins or antibodies that protect us against infectious agents. The doctor is guessing that a once a month injection would benefit Allie. This is a fix only that lasts 30 days is what I understand. This treatment would be for the rest of her life. We are looking more closely at this treatment to see if it will be right for Allie.
In Allie's IEP, Individual education plan, at the school has a special request to have the paraprofessional watch Allie wash her hands with soap and water every 2 hours during the school day. We have good reason for this...she has a broken immune system.
Micronutrient Analysis (WBC) DRAWN 2-28-12, Spectracell Laboratories, ordered by Dr. JK, determined the following deficiencies:
Vitamin B2, Vitamin B12, Folate, Vitamin C, Pantothenate, Choline, Fructose senstativity and Immnidex.
Age 8 1/2 this simple blood test was done. Allie was deficient in all of these items. Why didn't I push for this simple blood test at age 2? Why didn't the pediatrician think out of the box? This is the recommendations for her supplements:
- Vitamin B2 25 mg daily.
- Vitamin B12 500 mg daily (methylcobalamin or adenosylcobalamin).
- Folate 800 mg daily.
- Pantothenate 500 mcg daily.
- Choline three options: 500 mg bid from Choline Bitartrate, Citrate or Chloride salts. 4,000 mg daily of phosphatidyl Choline. Or 2 tbsp Lecithin daily.
- Frutcose sensitivity to avoid concentrated sweet foods with table sugar, sucrose, corn syrup, fruit juice concentrates, fructose, and foods rich in these ingredients. Whole fresh fruits are acceptable.
- Vitamin C 250 mg daily
- Immunidex is an evaluation of the patients T-lymphocyte's response to mitogen stimulation. Low responses may be related to the patients levels of stress, nutritional deficiencies, or pathology, Improvement in the patients Immunidex may be facilitated by correction of the functional deficiencies reported in this analysis. - Spectracell Laboratories, SpectaCell Data Services.